Wednesday, August 10, 2016

New findings and research methods leading to elucidation of fertilization mechanism

A Japanese research group has determined the crystal structure of the JUNO protein, an egg surface protein essential for fertilization. These structure-based mutational analyses elucidated a mechanism of the interaction between egg (JUNO protein) and sperm (IZUMO1) on a molecular level. These studies will provide a framework toward an understanding of the fertilization mechanism.

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