Zebras' vivid pigmentation and the fight or flight instinct. These and other features of the world's vertebrates stem from neural crest cells, but little is known about their origin. Scientists propose a new model for how neural crest cells, and thus vertebrates, arose more than 500 million years ago. They report that these cells retain the molecular underpinnings that control pluripotency -- the ability to give rise to all the cell types that make up the body.
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