First real-life trial finds oral cholera vaccine protects against endemic disease, could speed up global control efforts

An oral cholera vaccine (Shanchol) given as part of routine health services is safe and protects against severe cholera in children and adults in urban Bangladesh where the disease is endemic, according to the first real-life trial of this vaccine. The findings lend support to the use of the vaccine in routine mass vaccination programs to help to control cholera in endemic countries.