Friday, October 31, 2014

Ebola Outbreak Highlights Struggle for Science in Africa and Inequalities in Global Health Research

As authorities scramble to contain the spread of Ebola, it helps to take a step back and examine why the science has not kept pace. Despite some promising advances in immunotherapy, there remains a great deal we haven't learned about the virus. In part, the lack of research in "non-profitable" infectious diseases occurring in underprivileged countries has left threats like Ebola largely unaddressed. In addition, inequalities within the system of international scientific collaboration have hindered African researchers from leading the way against diseases ravaging their continent.

Similar concerns were echoed by the director of the National Institutes of Health, Francis Collins, who acknowledged in a recent interview that the quest for an Ebola vaccine in the United States had been slowed by a combination of lack of interest from the pharmaceutical industry and domestic budget cuts to basic research. With the arrival of the first Ebola patient on U.S. soil, however, the urgency to find a cure has hit home.

Nonetheless, individual states cannot be expected to replace what needs to be a coordinated effort. Speakers at a security meeting last month acknowledged that investing in Africa's ailing healthcare infrastructure, while necessary, was unsustainable. What is needed are African solutions aimed at paving the way for science-based economies. In the words of Dr. Nkem Khumbah, "Africa needs science, not aid."

Enter global health science. The past two decades have seen a rapid rise of academic programs in the United States under the label of "global health science" -- global health aimed at balancing the dual objectives of encouraging scientific collaboration opportunities with resource-poor countries and protecting against global health threats that disregard national borders. Its principles espoused notions of equal scientific partnership aimed at capacity building and leadership development in countries with limited resources.

For international researchers, collaboration was seen as a welcome opportunity to further their careers by publishing in high-impact journals that are almost exclusively found in Europe and the United States. A combination of domestic and international grants would allow African researchers to focus on diseases that are considered Africa-specific, such as tropical infections.

However, and despite promising indications that science in the continent is gaining momentum, the majority of local laboratories still fail to meet the basic requirements set out by the World Health Organization. Africans account for a mere 1.1 percent of the world's scientific researchers, and, more alarmingly, there are fewer than 5 million students of higher education in sub-Saharan Africa, a region with a population of more than 1 billion.

As the current Ebola crisis has highlighted, the funding, mentoring and research on Ebola are still performed in centers located in Europe or North America, which, as we have seen, is not always viable. There are few if any academic programs that are dedicated to the research of Ebola in Africa. So why hasn't the global health science initiative delivered on its promises?

In her book Scrambling for Africa: AIDS, Expertise, and the Rise of American Global Health Science, anthropologist Johanna Tayloe Crane traces the structural inequalities inherent in the system of global health science that have hindered progress on another virus: HIV. Science, as currently deemed legitimate by leading journals, has become increasingly "molecularized" and technologically mediated. In the context of today's global science, clinical expertise and other "qualitative" knowledge that has been acquired through years of exposure to a particular disease are considered less valuable. In the absence of specialized laboratories, many international collaborators often find themselves relegated to the role of "sample providers" and in some cases lose authorship.

Contrary to popular belief, philosophers argue that science is not socially neutral. The American philosopher Thomas Kuhn emphasized that scientific truth is defined largely by consensus within the dominant scientific community and undergoes periodic "paradigm shifts." As such, scientific truth is not determined by the linear accumulation of "objective" criteria alone and is heavily influenced by consensus within society. Nowhere is this influence more evident than in the arena of international scientific collaborations.

Under the header "Molecular Politics of HIV," Crane highlights how the research of HIV has, until recently, focused on a particular genetic subtype that is predominant in North America, Europe and Australia and has subsequently been used to establish all we know about antiretroviral therapy and drug resistance.

As a result, despite the noblest intentions of their counterparts in the United States, collaborators in underprivileged countries usually find themselves consigned to positions of dependency. Many complain that they are not involved in the planning of collaborative projects, their voices not heard and the structural challenges they face at home not acknowledged. For African scientists, this has often led to frustration and has had a detrimental impact on the amount of effort they are willing to invest.

The importance of allowing African academics to pursue equal career ambitions and become leaders at the international level cannot be understated from a health security perspective. Only then will these academics champion their own homegrown innovative solutions and create self-sustaining and robust health science infrastructures.

As Ruth Katz of the Aspen Institute writes on the current Ebola crisis:

For too long, the history of infectious diseases has been that of ignoring a threat until it nears disaster.... To get ahead of the curve, we need a renewed commitment to research and action, and enough resources to put more public health boots on the ground, both at home and abroad.

The global health initiative can deliver. However, its policy makers and leaders need to be conscious of the inherent inequalities within the highly competitive academic environment. Active steps need to be taken in order to ensure that the current collaborative system is more inclusive of the career aims and ambitions of those whose lives are directly affected.

Key to Prostate Cancer Resistance

… in most prostate cancer patients results in an initial regression of tumor. This … factor kappaB (NFkappaB) signaling in prostate tumor cells grown in culture or … the National Cancer Institute (CA076142). Categories · Cancer News · Cancer Research · Prostate Cancer · Urologic Cancers Previous post …

Lung Cancer Risks for Non-smokers

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State, Feds reach 5-year, $41B health-care deal

… Friday evening announced a five-year health-care deal with the federal government … for sharing our commitment to health-care reform." The overall deal … Center, Lawrence General Hospital, Signature Healthcare, Steward Health Care, Cambridge Health …

Key to Prostate Cancer Resistance

Trick to Prostate Cancer cells Resistance Oct 31, 2014 – 22:58 GMT Lookings for propose combination of therapies that may aid manage resistant prostate cancers cells October 31, 2014|Dikshya Bastakoty Prostate cancer cells. (Wellcome Photos) Androgen-deprivation treatment in most prostate cancer cells individuals leads to a preliminary regression of growth. [...] Read More

A Photo Tour: Chocolatiers in Brussels

I fly to Brussels every month so I decided to devote my recent trip to chocolate shops. The World Capital of Chocolate's cobbled back streets led me to shops where chocolate is elevated to an art form.

Belgium has been at the center of Europe's chocolate trade since the 1690s. With a million residents and about 500 chocolatiers, the average Belgian consumes over 15 pounds of chocolate annually.

Take a peek at some of the window displays:

Neuhaus opened its doors in 1857. In 1912, Jean Neuhaus Jr. created a chocolate that he named praline (a hard chocolate shell with a filling). This was to become one of the best known and most appreciated of Belgian creations worldwide. Jean's wife, Louise, invented the "ballotin" the cardboard chocolate box. Photo ©Susan Fogwell

Leonidas is one of the largest chocolate companies in the world.
Photo ©Susan Fogwell
Galler Photo ©Susan Fogwell
Galler's Window Display Photo ©Susan Fogwell
Photo ©Susan Fogwell
Photo ©Susan Fogwell
Photo ©Susan Fogwell
Photo ©Susan Fogwell
Photo ©Susan Fogwell
Photo ©Susan Fogwell
Photo ©Susan Fogwell
Photo ©Susan Fogwell
Photo ©Susan Fogwell
Photo ©Susan Fogwell

Major Police Group: Mandated Treatment Can Help Some Mentally Ill

The International Association of Chiefs of Police (IACP) approved a resolution calling for greater use of mandated treatment, commonly known as assisted outpatient treatment (AOT), at their annual meeting in Orlando, Florida. Research shows that AOT reduces arrest, suicide, involuntary hospitalization and violence by the most seriously mentally ill, all of which require a police response.

AOT allows judges to order a small group of the most seriously ill to stay in six months of mandated and monitored treatment while they live in the community. It is limited to those who have already accumulated multiple episodes of homelessness, hospitalization, violence, arrest or incarceration associated with going off treatment. U.S. Rep. Tim Murphy (R-Pennsylvania) included funding for AOT in the Helping Families in Mental Health Crisis Act (H.R. 3717). The National Sheriff's Association, the U.S. Department of Justice, and the National Alliance on Mental Illness (NAMI) previously endorsed AOT.

There are now 10 times as many mentally ill incarcerated as hospitalized. New Windsor, New York, Police Chief Michael Biasotti conducted a survey of 2,400 senior law enforcement officers and recently told

We have two mental health systems today, serving two mutually exclusive populations: Community programs serve those who seek and accept treatment. Those who refuse, or are too sick to seek treatment voluntarily, become a law enforcement responsibility.

He believes AOT will help return care and treatment of the seriously mentally ill back to the mental health system, where it belongs. Chief Michael Biasotti and outgoing IACP President Yost Zakhary were responsible for obtaining the IACP endorsement.

Uncertainties still dog rollout of health-care reform

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After breast cancer, holding on to hope of being a mother

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How Phytates Fight Cancer Cells

cancer cells, both estrogen receptor-positive and negative breast cancer cells, voicebox cancer, cervical cancer, prostate cancer, liver tumors, pancreatic, melanoma, and muscle cancers. All …

Chairmen: This is the health-care bill we intended

… committees that collectively authored the health-care reform legislation (Ways and Means … Act was designed to make health-care coverage affordable for all Americans … an empty, unfulfilled promise. Before health-care reform, the need for affordable …

35 Lessons Learned So Far on This Journey Called Life


If 50 is the "new 30" and 40 is the "new 20," I'm not sure where I fit on the age spectrum, but as I mark the beginning of my personal new yaer I took some time to reflect on a few lessons that I've learned along the way. I've gleaned these nuggets through picking myself up after I've fallen; reading countless self-help books; watching TV and Oprah; and by listening to my magnificent mom. One thing is for sure, if you're lucky, with age comes wisdom, confidence and empowerment.

1. Humans are a lot more alike than we are different. We all want to be loved, valued, and appreciated.

2. There's something special to be said about anticipation. Even in the present it's nice to have something to look forward to. So live in the moment, but have something in your back pocket.

3. Life can change in the blink of an eye (for the good or bad) so Carpe Diem.

4. We all need a good cry from time to time.

5. You can't choose your family but you can choose your friends... good friends really do make the world a better place.

6. People come into your life for a reason, season or lifetime.

7. "What do you do?" I'm not sure why that's one of the top three questions people ask each other after being introduced. We are so much more than "what we do."

8. All families have some type of dysfunction, drama or "that" relative so there's no need to be embarrassed or ashamed of your family.

9. Just because a person is your friend it doesn't mean you should travel with them. You can't travel with everyone.

10. When you move in gratitude the realization of what you have to be thankful for is simply amazing and the experiences, people and things you have to be thankful for multiply.

11. There will be crises... identity crises, the quarter life crisis, the everyone's getting married but me crisis, the my husband doesn't understand or appreciate me crisis, the midlife crisis. All crisis are temporary and when put into perspective really first world problems. This too shall pass!

12. The world is small... it use to be six degrees of separation -- now I think there about two degrees separating us from each other. It's astonishing how connected the world is.

13. There's something special about home, where and whatever you consider to be home. Home will and should always hold a special place in your heart.

14. Like Outkast said in their song, Sorry Mrs. Jackson there is a forever, forever ever, forever ever. Some things last an eternity, like trying to maintain a healthy weight. It's a forever lifestyle change when you're an emotional eater and yo-yo dieter like me.

15. Time really does heal all wounds.

16. It's important to have healthy boundaries in your relationships and you have to teach people how to treat you.

17. Yes, there are people you will never like and people that will never like you and it's okay.

18. Every woman needs at least one good girlfriend. Those they say they don't are lying!

19. Opposites attract. Find friends with complementary skills.

20. Youth really is wasted on the young.

21. A broken heart hurts like hell. The pain comes from the dream and plans that are to be unfulfilled or deferred.

22. We get to reinvent ourselves. The person you were in high school is not the person you are today, thank God, and the career you have today doesn't necessarily have to be the career you have for your entire life.

23. Like the caterpillar becomes a butterfly, if we are blessed, we evolve into our truest and best selves. (Sometimes it is not a pretty process.)

24. To be a friend you don't have to talk every day or even once a month... a real friendship can survive the curves, detours, distance and time called life.

25. In the great debate of nature vs. nurture. Nurture gets my vote.

26. The power of laughter... there's healing, release, tears, happiness and joy.

27. Fresh flowers are good for spirit... simple, beautiful and fragrant.

28. A bubble bath, hot shower, scented candle, nap or glass of wine can work wonders!

29. We have to learn to forgive ourselves for past mistakes, regrets and hurts because today is a fresh start with new opportunities.

30. Things may not go as planned but all things work as they should.

31. Some call it surrender. Sometimes you have to let things unfold or as they say... let it do what it do.

32. It's a big, huge and exciting world... travel, visit and explore.

33. Time and chance happen to us all... the key is being prepared when your chance comes.

34. Our parents fibbed. Words do and can hurt, so use them carefully.

35. God, The Universe, The Creator, whomever your higher power is, is so good! Here's to unexpected, undeserved mercy and grace..."AMAZING GRACE how sweet the sound that saved a wretch like me."

13 Foods That Are Saltier Than You Realize

Just because you can't taste it doesn't mean belly-bloating sodium isn't there. Here's how to spot the salt that's hiding in your diet.

Here's What People Had To Say About Food This Week

It's Halloween today, and that means candy. While most people have already gone out and bought their bags of sugary goodness, Josh Weinstein tweeted that he serves up prime rib instead. Your move, trick-or-treaters.

But forget Halloween and eating candy alone (lookin' at you, Josh Peck) -- Saturday is November 1, and that means that it's almost time to pick out the perfect turkey and tell family members what you're thankful for. For some, it could be all the different ways to style potatoes OR Chili's, T.G.I. Friday's and Applebees finally admitting they're basically the same restaurant. To each their own.

But for now, just forget about all the holiday madness. Sit back, relax, order a Starbucks via delivery (what?!) and enjoy your Friday.


How Phytates Fight Cancer Cells

Exactly how Phytates Battle Cancer cells Cells Today – 17:18 GMT Phytate is a substance found in grains, grains, nuts as well as seeds. The ordinary day-to-day consumption of phytate in vegetarian diet regimens meanses two times that of those eating blended diet regimens of plant as well as animal [...] Read More

Take A Peek Behind The Scenes At The Sriracha Factory

Sriracha has captured hearts and taste buds around the world, inspiring its own cult following. Today, you don't have to settle for slathering Sriracha sauce on your sandwich -- you can do it while wearing a Sriracha-logo hoodie and holding a Sriracha-flavored lollipop at a Sriracha-themed music festival.

But what goes on behind the scenes where the beloved condiment is made? A new video released by Zagat gives us a glimpse inside the Huy Fong Foods factory in Irwindale, California, and delves into some of the controversies surrounding the company's famous product.

Embarking on one of the daily factory tours that Huy Fong Foods now offers to the public, Zagat Editor James Mulcahy learns how the tangy magic happens and what the real story was behind those "Sriracha shortage" rumors. Owner David Tran even makes an appearance to explain the dust-up over the facility's "spicy smell," which some Irwindale residents claimed caused headaches, heartburn and eye irritation.

The factory has hosted about 2,000 tourists so far, which is more than the population of Irwindale.

Sign us up! We're curious -- and hungry.

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How brain cancer sent one woman 'over the edge'

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Using Your Words to Reach Your Business Goals

source: IStock

Your words literally have creative power and the ability to transform your life. Many people don't realize that their level of success is directly connected to the words they are saying every day. In my office, we have a saying: "If anything can go well, it will!"

You have an amazing force at your disposal that can help bring you the life that you want: your mouth! You can speak life, happiness and prosperity into physical existence just by opening your mouth. Begin to say something in the direction of your dreams. Your words create your world. If you change what you say, you can change your life's outcome.

With the power of positive affirmations, you can create the successful life and business that you want. The key is to focus on what you want instead of what you do not want. Every day, we're creating our world with words fueled by our own emotions. Every word that you speak is either bringing you closer to your goals or taking you farther from them. This is why positive affirmations--intentionally speaking positive statements every day-- are so important to your success. For example, "I will bring in 10 new clients this month" is better than saying, "I don't lose any clients this month." The positive phrase will cause you to focus on bringing in new clients, while the negative affirmation will cause you to focus on losing clients.

What will positive affirmations do for you and your business?

1. Help you to focus your mind to achieve your business goals. Rehearsing positive statements aloud reminds you of what to focus on and keeps your thoughts in line with your goals. The more you hear positive statements of achievement and success, the more you will believe it and eventually achieve it.

2. Help you to filter your daily conversation to ensure it supports your goals. Once you begin speaking positively about your business goals and dreams, you become more conscious of your conversation and will make a deliberate effort to avoid counteracting positive statements with negative ones. Many people are often amazed at how negative their conversations can be throughout the day. Affirmations will help you to tweak your talk to stay on target with your desired outcome, by putting a positive spin on it.

3. Help you paint a picture of your desired outcome on the canvas of your imagination. Words are visual. Every word evokes imagery, so it's important that you speak positive, vivid words that ignite your vision of success and achievement.

Say affirmations about what you want to have, do, be, see and experience. Don't limit yourself. As you begin to say your daily affirmations, you will find yourself believing them more and more. Your mind will then begin to subconsciously look for ways to accomplish these things and you will begin to attract what you say into your life.

When speaking your affirmations, use positive statements like the following:

  • "I am a creative thinker who makes money from my ideas."

  • "My business is growing and expanding every day."

  • "Making money is easy!" This one is a personal favorite and I even had drinking cups made with this affirmation on them. My staff and I are always working to increase our water intake, and so the cups are perfect to keep us focused and motivated each time we take a sip of water--they literally are "Sip 'n' Say" cups that prompt you to speak this positive statement aloud as you use them throughout the day.

Affirmations are probably one of the easiest success tools you have at your disposal that you can take fast action on and implement right away. Here are a few tips to getting started...

Take out your goals list and begin to declare your success. A positive affirmation is simply talking with expectation about your desires. You can write an affirmation in declarative statements using the present tense to verbally express your desired outcome in your business. Always speak in the present tense, like it is already happening. Your words have powerful creative ability, so it is important that you speak what you desire on a daily basis. Keep saying it until you believe what you are saying in your heart and mind.

My Successful Woman Affirmation Program will help you create a thriving business with the words you speak daily. By listening to the audio and repeating the affirmation, you can recondition your thinking and break down the barriers that hinder your success. You will simultaneously attract prosperity, success and fulfillment like you never have before.

Surround yourself with positive people, have positive conversations and take a break from negative news. To protect your positive mind and atmosphere, refuse to say, hear or agree with any negative words--especially about your business or income. Instead, flip the switch and replace all negative expressions with positive ones. Speak statements that create positive energy, perpetuate a positive outlook and build positive expectation--you need expectation and hope to reach your goals in business.

Start saying what you believe in the present tense.
Don't put everything in the future tense; say it like it's happening right now: "I am now manifesting what I want!" Focus on the good, expect good things to happen for you and you'll see that more good will come your way. It can be something simple as saying: "I easily and effortlessly attract positive situations, opportunities and uplifting people into my life that cause me to have a flood of goodness daily!"

For the next 30 days, challenge yourself to make a conscious effort to watch your words and speak only positive statements. Stop yourself from saying anything negative. It might feel strange at first, but it will become easier as the days go by. Soon, positive affirmations will be so natural that they are built into every conversation that you have. This principle can be summed up like this: Say it ... say it like you believe it ... say it like it's happening right now--and your business will be impacted like never before.

Panel to probe Brisbane asbestos deaths

… old Wunderlich asbestos factory at Gaythorne. Pic: Darren … and a contaminated creek nearby and took broken sheets of asbestos … data from Cancer Council Queensland’s cancer registry and the national mesothelioma … as Panel to probe Brisbane asbestos deaths

Lecia Sequist, MD, MPH, Is Named November LUNGevity Hero to Kick Off Lung Cancer Awareness Month

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Morrisville jeweler honors breast cancer survivors

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Himalayan Viagra fuels caterpillar fungus gold rush

Overwhelmed by speculators trying to cash-in on a prized medicinal fungus known as Himalayan Viagra, two isolated Tibetan communities have managed to do at the local level what world leaders often fail to do on a global scale -- implement a successful system for the sustainable harvest of a precious natural resource, suggests new research.

No detectable asbestos at Vic site: EPA

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£2m surgical robot to help cancer patients

… to treat a range of cancers including prostate, bladder, cervical, liver, pancreatic … . He had his prostate removed on September 11 after cancer was detected … have had robotic surgery for prostate cancer.”

This Halloween, Let's Protect Kids From the Deadliest Demons

With Halloween just around the corner, little goblins and ghosts are preparing for the eeriest evening of the year. Their spooky costumes are ready and their jack-o-lanterns carved, witch cackles practiced and down to an art. But when trick-or-treaters take to the streets tonight, the most spine-chilling horror will be nowhere in sight.

That's because you'd need an angiogram to see it . The most frightful fact you'll hear this Halloween is that by the time they're old enough to walk door to door collecting candy, children in America show the precursors of heart disease. Artery-clogging plaque is already lurking in their blood. You'd never know it, but their fate has been sealed: Perhaps as many as half of all kids will eventually succumb to the country's leading killer.

The story is even scarier for obese children who, new research shows, have all the warning signs when compared to children of a normal weight: higher blood pressure, higher fasting glucose levels and insulin readings, higher triglycerides, higher total cholesterol, lower HDL ("good" cholesterol) and higher LDL ("bad" cholesterol). These are the telltale signals of a sickness that, until fairly recently, had only been seen in older adults.

Heart disease and obesity aren't the only ghouls haunting our country's children. Type 2 diabetes -- also once believed to be a uniquely adult disease -- is more common than ever in kids. As many as one in three children born at the turn of the century will be diagnosed with diabetes, and that ratio jumps to one in two when it comes to children of color.

The good news is that there are ways to keep the Grim Reaper at bay. Starting tonight, we can help our children lead healthier lives by opting for sweet and savory treats that will please even the pickiest little monsters. Instead of the regular candy bars, which are high in saturated and trans fats, make your own spooky goodies using healthful, plant-based foods. Try a new take on the classic caramel apple or whip up some ghastly tortilla chips and ghoul-camole.

Even better, take your healthy Halloween a step further by returning to the holiday's roots -- traditionally, All Hallows' Eve was a day to abstain from meat. Meat and other animal products, such as dairy and eggs, are the biggest sources of fat, calories, sodium, and cholesterol in children's diets, and animal products are linked to increased risk of heart disease, Type 2 diabetes, obesity, and cancer. A whole-food, plant-based diet reduces the risk for all of these illnesses, and its near-supernatural powers can even reverse the damage that has already been done.

Of course, cutting out candy, meat, and dairy products just one day a year won't do our children any good. In the United States, every day is like Halloween -- the pressure to eat foods that make us sick is never-ending. Children are spellbound by TV advertisements for fatty fast food at home and fed mystery meat and chicken nuggets in their school cafeterias. They become zombies in a consumer culture that puts food industry profits far above their health.

But with a little creativity, holidays like Halloween could become opportunities to teach kids that healthful eating can be both fun and delicious. While we can't save them from every villain, we can cast a healthy spell that will protect them from the worst of the real world's dastardly demons.

DARA BioSciences Continues to Support Patient Outreach and Education in Conjunction With Breast Cancer Awareness Month

… treatment of metastatic breast cancer, the adjuvant treatment of node-positive breast cancer in postmenopausal women, the reduction in risk of invasive breast cancer … incidence of breast cancer in women at high risk for breast cancer. Currently, there …

The 13 Greatest Destination Food Towns In America

Eating is probably the greatest excuse we've ever heard for planning a trip. But as a responsible foodie traveler, you want to make sure you're visiting a town with a local culture as rich as the jambalaya on the table.

We were thus ecstatic when Saveur released its annual Culinary Travel Awards, naming America's best culinary towns with populations under 800,000.

These towns play host to not only delicious dishes, but also delicious scenery, bars, hotels and places to explore. In fact, they're some of our favorite towns, too.

Betcha can't visit just one.

New Orleans, Louisiana
NOLA won Savuer's "experts' choice" award, earning top marks for not only its famous Creole food but also its lesser-known Vietnamese scene. Very un-touristy oysters and French bread are dished up at the historic Roosevelt Hotel -- be sure to tour the Crescent City Farmers Market, Algiers Point and the Garden District between meals.

Portland, Oregon
Saveur gave Portland the "readers' choice" award for its world-class chefs, stellar wineries, funky small-town menus and awesomely small-town meal prices. Saveur points out that the city is a delicious, kitschy mash-up -- you'll find funkadelic bubblegum donuts at Voodoo and "food cart pods" dishing out everything from porchetta sandwiches to goat cheese with almond butter. Visit Powell's City of Books or take a drive to Forest Park for burbling creeks and hikeable trails.
portland oregon beer

Seattle, Washington
Of course coffee comes to mind, but Seattle has also gotten to be one of Saveur's "outstanding" towns for its beer, donuts and friendly neighborhood cafes home to top-notch pastries. Pike Place is a foodie's dream -- and after sightings of a marijuana food truck, things only get more interesting.

Charleston, South Carolina
Where do we even start -- the Nasty Biscuit at Hominy Grill? The pastrami sandwich at Butcher & Bee? One thing is for certain: Charleston is a perfect foodie vacation, as you won't find such a perfect blend of down-home, Southern-inspired, locally-sourced eats anywhere else. With streets of quaint shops and historic waterfronts oozing Civil War lore, you'll have plenty to see between meals, too.

Boston, Massachusetts
With cheap brewery tours and some of the best bartenders in the country, Boston is the perfect place to cozy up with a pint (or bar hop between MANY pints) when cool weather hits. Local farms vend fresh ciders, cheeses and veggies for a cheap meal while you ice skate, ghost tour or take a leaf peeping day trip. Oh, and don't skip the chowda at The Daily Catch.

Atlanta, Georgia
You probably didn't know Atlanta had the "world's largest drive-in restaurant"... or that you could bike from just outside Atlanta to Alabama on the Silver Comet Trail. Luckily, these two activities -- binging and biking -- go hand-in-hand. But for a more refined experience, check out Atlanta's upscale takes on classic comfort food, like outstanding grits with Andouille sausage and the best grilled cheese probably ever.

Washington, D.C.
When Bill Cosby and President Obama dine at the same chili bowl dive, you know it's got to be good. D.C. is obviously a perfect weekend vacation for its historic sites -- check out November's FotoWeek and nearby Alexandria Film Festival, too! -- but it's also a bustling foodie town, with offerings for both early-rising workers and late-night carousers -- we're gonna need the chorizo risotto at Tico, STAT.
washington dc restaurant

Asheville, North Carolina
Asheville is having a major "moment," most notably for its handfuls of breweries and a used book exchange that pairs wine with literature. Everything is innovative here -- you'll find snacks like house-made potato chips and sturgeon with mustard on an Asheville eating tour, and dinner options include everything from Spanish tapas to vegan cuisine. The gardens, meadows, ponds and forests of the very castle-like Biltmore Estate are a regal place to hike off those hops.
biltmore estate

Honolulu, Hawaii
Even if the ocean didn't exist, the loco moco would still be reason enough to visit Oahu -- this island delicacy is part eggs Benedict, part rice dish, part poutine and ALL parts satisfying. It's a symbol of Hawaii's spot at the nexus of Asian and Western cuisine cultures -- a trend coming to fruition as the city undergoes what Conde Nast Traveler calls a "culinary revolution" (did someone say macadamia nut pizza?!). While you're in the state capital, visit the Honolulu Zoo and hit the beach.

Providence, Rhode Island
How could a town with so many donut shops per capita not be a top foodie destination? The city is also extremely walkable, making it easy for visitors to hop from boat tours to the RISD Museum to the historic State House. End your day in a hidden bar in Federal Hill or with fresh lobster ravioli made by hand.

Minneapolis, Minnesota
Minneapolis is one of our favorite rising cities, with a booming social scene including live music, vintage shops and sports teams galore. It doesn't hurt that it's also home to the most whimsical pastries on Earth and some super-affordable restaurants. A local favorite is hot dish, an irresistible skillet dish with many renditions across the city.

Portland, Maine
Local cuisine is king in Maine's coastal food town. The innovative Vinland restaurant serves only local ingredients -- waiters are outfitted in locally-made duds, and the interior is decorated with white birch, too. Enjoy just-caught seafood, Asian-inspired buns and fresh breads at dozens of renowned restaurants, or make a day of picking out dinner at Harbor Fish Market.

Louisville, Kentucky
If you thought bourbon, you're right -- you'll find bourbon slushies, bourbon cocktails and straight-up libations in and around the famous Bourbon Trail, which makes it easy to soak up culture and beverages at the same time. Old Seelbach Bar, which was once a frequent haunt for F. Scott Fitzgerald, has a slew of rare bourbons... but don't worry, Louisville offers farm-to-table entrees, Mayan-inspired dishes and ooey, gooey Hot Brown sandwiches too.

Research and Markets: Brain Cancer (Glioblastoma Multiforme): Disease and Pipeline Analysis Report

Research and Markets: Brain Cancer (Glioblastoma Multiforme): Disease and Pipeline … the addition of the "Brain Cancer (Glioblastoma Multiforme): Disease and Pipeline … new market research report titled Brain Cancer (Glioblastoma Multiforme): Disease and Pipeline …

£2m surgical robot to help cancer patients

₤ 2m medical robotic that can help cancer clients Today – 10:22 GMT New ₤ 2m robot at Leicester General Healthcare facility Remarks (0) A new ₤ 2 million medical robotic has started running on cancer cells clients in Leicestershire. The equipment, mounted at Leicester General Healthcare facility, has robotic [...] Read More

Thursday, October 30, 2014

ONO PHARMACEUTICAL : Phase 2 Objective Response Rates and Survival Data for Opdivo (nivolumab) in Heavily Pre-treated Advanced Squamous Cell Non-Small Cell Lung Cancer to be Presented at the 2014 Chicago Multidisciplinary Symposium on Thoracic…

… types overseas, including: Non-Small Cell Lung Cancer (NSCLC), Renal Cell Carcinoma (RCC … patients with refractory squamous cell lung cancer after their disease has progressed … for Human Use (CHMP). About Lung Cancer Lung cancer is the leading cause of …

WCSU teams rally for coach battling brain cancer

… who has been diagnosed with brain cancer. "I know it seems …

10 Annoying Food Trends That Need To End Now, Immediately, Pronto

When it comes to food, we are not hard to please. Ask anyone. We will pretty much eat anything that comes within a few yards of our mouths.

So, when we say that we’re no longer hungry for a certain food trend, you know there’s a big, big problem. We partnered with Mucinex®, the brand that's all about ending the misery in your life, to call out the most obnoxious trends.

You're on notice, chefs. End these trends. End them immediately.

Kale Creep
Don’t get us wrong: kale is a lovely green thing. When we’re in the mood for veggies, we turn to kale. But recently we have noticed that kale is everywhere. We can't take a bite out of a chip or a nibble from a cupcake without tasting it. We worry where will it turn up next. Our birthday cake? Our toothpaste?

Stop the spread now -- before it's too late.

Juice Cleanses, AKA the Liquid Method for Slow Starvation
No one needs juice to cleanse their body. A body is a giant, walking trash compactor with a self-cleaning function. It is literally cleaning your insides while you read this. Also, spoilers: no one is losing that much weight because, during a cleanse, metabolism slows to a crawl. Instead, the juice cleanse is just making everyone insanely cranky. With hunger.

That makes us cranky. Quit it.

In the old days pumpkins only came out around the holidays, usually in delicious pie form. Now we have pumpkin beer, pumpkin latte, pumpkin pasta, and, somehow, pumpkin-spiced foie-gras mashed-potatoes.

Keep pumpkins in our pies, our soups and our front stoops. Nowhere else.

The “New” Quinoa
We literally just figured out how to pronounce “quinoa,” and now we’re already expected to move on to the next ancient supergrain? Freekeh? Kamut?! TEFF?!?

No. We refuse to try anything else. If you need us, we’ll be rocking in the corner, clutching onto bags of white rice.

Food Being From a “Farm”
Of course it comes from a farm. It is food. It does not grow in factories or warehouses or depots or mixed commercial/residential property. No, really -- where else would food grow but a farm? Find a better way to say that food is fresh. For instance, use the word "fresh." Please.

Pretending That The Paleo Diet is Incredibly Healthy
We like grilling and consuming vast amount of meats, we really do. But let’s not indulge in the fantasy that it’s wise to copy the exact eating habits of a group of proto-people whose average time on this Earth was, oh, say, 22 years. (Especially since the healthiest people on Earth eat tons of the Paleo-forbidden rice.)

You know how a caveman would feel about a plate of spaghetti? Ecstatic. Stop Paleo.

Excessively Gendered Foodstuffs
We are not entirely sure why the plastic package of salad we buy in the grocery store needs to be called “Girl Greens.” Is it less-than-manly to eat a piece of spinach, we ask you? Is that not what Popeye did to grow his muscles to obscene size? Women can eat steak. Men can eat yogurt.

Degenderize immediately.

Putting Everything In Mason Jars
This was super cute when the struggling dive down the bar did it! But the folksy charm is somehow lost on us when the restaurant with the $27 burger is using a mason jar to serve us our bill. And don’t dare serve us a salad or a dessert in one.

Fancy restaurants have way more money than Grandma. Stop stealing her dishware.

Instagraming Foodstagrammers
This is not as funny or as smart as the Internet thinks. At least the person taking pictures of food has, you know, a pretty picture of food. The person taking pictures of the person taking pictures probably only has a picture of some bearded, tight-pantsed stranger cluttering up their phone’s storage space. Leave the hipsters be.


We're hip. We're not opposed to fusion. For instance, fusion power seems like a pretty good idea? And we listened attentively that one time Jay Z and Linkin Park made that CD together. But this reckless orgy of experimentation must stop. We do not want our ramen turned into a dessert or a burger. We cannot stand idly by while chefs destroy the already Platonic perfection that is the bagel.

End the trends now. We are not kidding.

Is there another food trend deserving an early retirement? Let us know in the comments.

Ask Mark Zuckerberg Anything During His First Public “Community Q&A” On Facebook Nov 6

1798717_824010997656677_1003455886952412230_n Most people have a burning question to ask about Facebook, whether they’re one of its 1.35 billion users or not. So taking a cue from Reddit’s Ask Me Anything sessions, Facebook’s CEO Mark Zuckerberg is upping the transparency and will play customer support himself on November 6th when he does Facebook’s first “Community Q&A”. The hour-long… Read More

Support Soda Taxes: Avoid Premature Aging

I was summoned to the emergency room stat. We tried unsuccessfully for more than 40 minutes to resuscitate the patient. Death by heroin overdose. The young man was 43. I had just started my work for Kaiser Medical Center in Richmond. The year was 1981.

"Forty-three, so young," I remarked to the seasoned ER nurse I was working with. She had vastly more experience than I. Her reply: "It's not the years, it's the mileage."

And so it is with our health. Our circumstances cause us to experience the "slings and arrows of outrageous fortune" as well as the more mundane stresses of everyday life differently. It is the social environment and our relative position within it that most determines the course our life will take, what options are open to us, and how long we will live. We human beings are exquisitely sensitive to social position, even if much of that awareness is unconscious.

ZIP Codes Trump Genetic Codes

It turns out that the average income of one's ZIP code is a more powerful predictor of life expectancy than one's genetic code. For every step up the social ladder, there is a corresponding increase in average life expectancy.

When asked to explain why social position determines health outcome in such a step wise fashion, Sir Michael Marmot, perhaps the world's leading authority in this field, put it this way:

The lower individuals are in the social hierarchy, the less likely it is that their fundamental human needs for autonomy and to be integrated into society will be met. Failure to meet these needs leads to metabolic and endocrine changes that in turn lead to increased risk of disease.

When our fundamental human needs for autonomy and belonging are not met, our physiology rebels. Stress hormones can increase and stay elevated. Eventually, this hypervigilant state can wear us down, and premature illness and death can result.

But there is more. There is our behavior. Heroin is a potent pain killer. For some, day-to-day life is terribly painful, and heroin makes it tolerable. In a lesser way, the same can be said for cigarettes. Nicotine is a powerful drug. Our bodies have receptors for it. Nicotine can pep us up when we are down, lessen our hunger, and relax us when we are tense. No wonder it's easier to give up the habit if we are less stressed out and have greater resources at our disposal.

We know that these harmful behaviors come with a price. In the case of the heroin addict, it cost him his life. It can do the same to cigarette smokers.

We are also learning that dietary choices are influenced by our social position. Coke and Pepsi target minority youth in their advertising campaigns in order to increase sales. Their ads equating soda consumption with happiness, success, popularity, sex appeal and athletic prowess are effective despite the mounting scientific evidence linking sodas and other sugary drinks to an astonishing list of chronic illnesses including Type 2 diabetes, obesity, heart attacks, strokes, high blood pressure, dementia, fatty liver disease, and some cancers.

Soda is not heroin, and soda is not tobacco. There are obvious and important differences. But consider this: Sodas are arguably a greater risk to the health of our children than either tobacco or heroin -- more than one-third of our kids will get Type 2 diabetes, and soda is a major culprit.

Sodas, Like Cigarettes, Can Make Us Old Before Our Time

If that doesn't get your attention, scientists have uncovered even more worrisome news about soda: It can age our cells prematurely just like cigarettes do.

There is something at each end of our chromosomes called a telomere. It is a DNA-protein cap which protects the DNA, our genetic material, from damage. Each time our cells divide to form new cells, telomeres shorten. Eventually the telomeres become too short for the cells to function normally and these cells die or malfunction. Measuring telomere length is one way scientists study cell aging. They not only shorten as part of normal biologic aging, but also from behavioral stresses like cigarette smoking or caring for a chronically-ill child. In other words, telomere length is a way of looking at, as the ER nurse put it, "the mileage."

It turns out that the more soda you drink, the shorter your telomeres. Over time, drinking a 20-ounce serving of soda a day ages cells about the same amount as tobacco smoking.

Our Chance to Make a Real Difference

Enter the Soda Tax Wars. Full disclosure. I'm a veteran. I ran the Richmond, California Soda Tax Campaign. I flew to Mexico to help lobby for the successful passage of the Mexican Soda Tax. I am working to help pass the Yes on D (Berkeley) and Yes on E (San Francisco) Soda tax efforts.

If you needed another reason to vote for these local soda taxes, remember that: Soda could age us prematurely, just like cigarettes. If we want to promote a healthy community we need to decrease soda consumption just like we have done with cigarettes.

Yes on D in Berkeley
Yes on E in San Francisco

Let's help our kids live long and healthy lives!

Male Patients Feel Forgotten in Breast Cancer Battle

Cancer survival rates slip back as too many sufferers diagnosed in A&E not by GPs

… thyroid, Hodgkin lymphoma, testicular and mesothelioma – have got worse in … diagnosed with cancer in A&E when the disease is … for brain, lung, liver, pancreas and stomach cancer are below … bodies mostly ignore bladder cancer. A combination of late …

CFOs Feel Powerless When It Comes To Managing Healthcare Costs, Poll Finds

… $620 billion each year on healthcare costs, and nearly half of … help fix the broken healthcare system. Rising healthcare costs place a huge … healthcare spending. Even more, 90% agree that if their company’s healthcare

In 2023, Medivation/Astellas Pharma’s Xtandi Will Be the Top-Selling Agent in the Prostate Cancer Market Across the United States, Europe, and Japan

In 2023, Medivation/Astellas Pharma’s Xtandi Will Be the Top-Selling Representative in the Prostate Cancer cells Market Across the … Today – 17:08 GMT BURLINGTON, Mass., Oct. 30, 2014/ PRNewswire/– Decision Resources Group discovers that Medivation/Astellas Pharma’s Xtandi will be the sales-leading representative across the globe’s major markets for prostate cancer, [...] Read More

Instagram Video Ads Go Live Because Everything Good Must Come To An End

Screenshot 2014-10-30 12.58.04 Instagram has at long last debuted video advertisements after rigorous testing and hands-on work with brands. And because they are advertisements, none of that rigorous work really matters because we simply hate advertisements. With video ads, the potential for high levels of suckage is high, as brands have a total of 15 seconds to capture you, as opposed to the half-second glance they get with… Read More

Brain Cancer Cases Shot Up In this Florida Town—Is a Defense Contractor to Blame?

… of whom were diagnosed with brain cancer between 2005 and 2007. Based … the signs and symptoms of brain cancer to increase early detection. Alonso … who had developed tumors and brain cancer. * * * Definitively proving the cause of … an especially lethal form of brain cancer called glioblastoma—the same kind …

This Woman's Post-Cancer Transformation Was 33 Years In The Making

Every breast cancer survivor's journey to accept his or her post-cancer body is different. For this survivor, it took 33 years to decide she was finally ready.

Rosemary Vaughan was diagnosed with breast cancer in 1981, but it wasn't until recently that she was finally able to tackle the last stage of her recovery: accepting her identity as a survivor.

"For a long time, I was not comfortable in expressing and sharing my experiences," she told HuffPost Live's Nancy Redd. "And with the help of my family and my children, they have given me a lot of strength and comfort to be able to come out of my box."

For Vaughan, that meant covering her mastectomy scar with a nipple tattoo, a growing trend among survivors. She got tattooed just an hour before her conversation with HuffPost Live, when she sat alongside her artist Vinnie Myers and explained the joy of finally being able to accept herself.

"I've waited a long time, and I don't think back then was the time for me to have had the tattoo, my nipple tattoo," Vaughan said. "I think that this was the time for me, and I'm so excited. I can't wait to show everybody, my family [and] my children. And buy a sexy bra."

Watch the full interview on accepting your post-cancer body here.

Sign up here for Live Today, HuffPost Live's new morning email that will let you know the newsmakers, celebrities and politicians joining us that day and give you the best clips from the day before!

Medicare Costs Analysis Indicates Need for Decreasing Use of Biopsies as Diagnosis Tool for Lung Cancer

… the lung cancer diagnostic workup prior to the introduction of major lung cancer screening … with lung cancer and $3,558 ($23,089) for those without lung cancer. Among patients not diagnosed with lung cancer, the median …

Program encourages NY health-care workers to go to Africa

… announced a program to encourage health-care professionals to travel to West … by offering them job and health-care protections upon their return. The … countries ravaged by the disease. Health-care groups and President Obama have …

Axalta Coating Systems Employees Celebrate Breast Cancer Awareness Month

… . Axalta Coating Systems Employees Celebrate Breast Cancer Awareness Month Axalta’s North … liquid and powder coatings, celebrated Breast Cancer Awareness month by wearing pink … affected by breast cancer. Axalta Employees at Front Royal Plant Celebrate Breast Cancer Awareness …

Your Favorite Characters Frozen In (Chocolate) Carbonite (PHOTOS)

Mmmmm horrific cruelty!

Photographer Henry Hargreaves froze some of his childhood idols in edible carbonite.

"In my nostalgic fantasy... the ruthless gangster, Jabba the Hut, put out a bounty on my favorite childhood characters," Hargreaves wrote in an email to The Huffington Post. "They suffer the same fate as Han Solo did in Return of the Jedi and are hung as trophies on his wall, all frozen in carbonite. But in my grown up world food has replaced fantasy as my obsession so here they are all made from chocolate."

Take a look at the photographer's creations below and watch his video above.

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About.Me Launches App That Aims To Replace The Business Card

american-psycho-business-card-scene1 Tony Conrad, the founder of, says it’s time to disrupt the business card. He’s released a new app today called Intro to do just that. “You don’t always have a business card with you, but you always have your phone,” Conrad explained over the phone. “This takes what we have with and makes it a digital business card for mobile,”… Read More

Chili Pepper Slows Lung Cancer Tumor Growth

… scientists focused on small cell lung cancer, a fast-growing type that makes … growth with human small cell lung cancer cells. Half the animals were … for patients with small cell lung cancer." The study was funded … apoptosis in human small cell lung cancer via the TRPV6 receptor and …

Cancer survival rates 'improving'

… is 90% for testicular cancer. Recently diagnosed prostate cancer patients will see a … %. High survival rates for prostate cancer and breast cancer are thought to be … of cancer," he said. "Lung, pancreatic, oesophageal cancer and brain tumours

Breast cancer researcher wins 2014 Aubrey J. Tingle Prize

… models, high-throughput screens, and translational breast cancer research. Created in honour of … of breast cancer tissue, have had far-reaching impacts on diagnosing and treating breast cancer.” His most recent work on the molecular taxonomy of breast cancer

Here Are Photos Of Taylor Swift Enjoying A Beer At A New York Knicks Game

Taylor Swift has been honest about her thoughts on alcohol, telling Esquire magazine in 2012, "If it doesn't taste like candy or sparkles, I usually don't drink it."

Well, clearly beer tastes like candy or sparkles to T-Swift because here are photos of the "Out of the Woods" singer sipping an ice-cold brew with her BFF Karlie Kloss at the Chicago Bulls vs. New York Knicks game at Madison Square Garden on Wednesday:



The gal pals even shared a few laughs with Ben Stiller and his son, Quinlin:

taylor swift karlie kloss

quinlin stiller

Swift's been having quite the week, with her new album, "1989," debuting to rave reviews on Monday. And it appears the night out at the game in New York City didn't leave her with a hangover. On Thursday, she rocked the stage before a huge crowd on "Good Morning America."

Good Morning America! Times Square! AHHHHHH!

Taylor Swiftさん(@taylorswift)が投稿した写真 -